Question 1) What is Rational Drug Use (RDU) ?

As identified by WHO in 1985 at Nairobi Rational Drug Use is “Patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community.”.

For a given indication appropiate drug can be choosen  rationally only if efficacy, safety, cost and suitability criteria are considered.

Question 2) Why Rational Drug Use is  necessary?

Rational Drug Use, primarily aims to watch over public health and benefits of society Inappropriate, unnecessary, ineffective and high cost use of medicines causes worldwide problems. Problems such as; prescribing drugs discordant to up to date guidelines, inappropiate prescribing for special patient groups, unnecessary use of expensive medicines, unnecessary use of antibiotics or parenteral formulations, giving insufficient information on medications to patients by doctors or pharmacist, administration errors of medicines by health personel, infrastructure defects in drug production or distribution  that facilitate the medication errors, indicates the importance of rational drug use.

Question 3) Things to consider in rational drug use

Primarily, identification of patient problem and accurate diagnosis of patient is mandatory. In parallel  identification process of effective treatment with or without medicines, If treatment includes medication; choosing appropiate drug, dose and duration of treatment steps should be followed. Prescriptions should be based on approved up to date guidelines.

Physician should  question current and recent medications of  patient.

Patients/caregivers should be informed about possible side effects of medications and food-drug interactions.

Extra caution should be taken when prescribing to; pregnant or lactating mothers, children and elderly, patientes with renal or liver failure, patients with drug allergy.

Drugs should be kept out of reach and out of sight of children in their orginal package.

The drugs with opened package should not be purchased. Drugs should not be used after expiration date.

Question 4) What does irrational drug use covers?

Irrational drug use includes:  unnecessary and excessive use, choosing treatment discordant to clinical guidelines, improper preferring of new drugs, imprecise behaviour in drug use
(route of administration, dosage, duration), improper personal drug use,  unnecessary use of antibiotics, unnecessary prescription of parenteral formulations, unnecessary and improper use of vitamins, improper use of food additives and herbal products, ignoring  drug-drug, and food-drug interactions. Irrational drug use causes, decreases in patients complience to treatment, drug interactions, development of tolerance to treatment, recurrence or prolongation of disease, advers reactions and increase in cost of treatment.

Question 5)  What are the errors in the implementation of Rational Drug Use?

Errors in the implementation of Rational Drug Use are:

  • Errors or defects in defining the problem of patient,
  • Wrong diagnosis,
  • İmproper choose of drug and treatment,
  • If treatment includes drugs, errors or defects in prescribing,
  • Improper dosing,
  • Wrong drug,
  • Errors in marking, labeling or informations on drug package,
  • Problems in communications with patient,
  • Lack or defects in information for treatment process, drug use, storage of drug and side effects.
  • Lack of patient compliance

Question 6) Which activities on Rational Drug Use are conducted in our country?

Rational Drug Use (RDU) covers many processes from production to distribution and disposal. Turkish Medicines and Medical Devices Agency Department of Rational Drug Use determined representatives of Rational Drug Use to ensure coordination in 81 provinces. According to Hospital Service Quality Standards, RDU teams are created in hospitals for planning and activities.

Different activities are being conducted to increase the awareness of the public and health professionals and behaviour change. Activities are carried out under the headings of promotion, training, evaluation and monitoring, administrative regulations.

Question 7) Who are the responsible parties for the provision of Rational Drug Use?

  • Physician who choose the drug,
  • Pharmacist who supply the drugs in appropiate conditions and  who gives drug consultation,
  • Nurse who administer drug,
  • Other health personel,
  • Patient / care givers,
  • Pharmaceutical industry,
  • Regulatory authorities,
  • Profession organizations,
  • Others (Press, academic)

are the responsible parties for rational drug use

Question 8) Definition of Pharmacist according to Rational Drug Use Principles

Rational Drug Use is using the right drug, for a proper duration, in right dosage, through the correct route of administration with adequate explanation and affordable cost for prevention, cure or control a disease. Pharmacist in accordance with the principles of Rational Drug Use; provider of the drugs for patients who have received special training and expert at the art of preparing medicines.

Question 9) Does pharmacist attention on Rational Drug Use has  effect on treatment ?

Patients  last encounter with a health Professional  usually occurs with  pharmacist.  Hence the importance of the information provided by the pharmacist to the patient is great.

Made as required by the pharmacist process of meeting the particular recipe, after adequate disclosure and marking in accordance with written instructions and brief drug product information is important to be available to patients on prescription drugs. To understand the nature of the patient’s illness, what is given to the drug, how to understand that you should use as the most important factors that increase treatment compliance. The drug is prescribed, the rational use of the process until the conclusion of the use and treatment of the patient are the most important and easiest step pharmacies may increase the patient compliance.

Question 11) What are the recommendations for patients use of medicines?


  • Should use the drug in the proper route of administration, at the right time range, in the right dose and use for a specified period of time without interruption.
  • When cutting yourself feel good drug should be spontaneous.
  • Notify the doctor should not benefit from the drug.
  • thought absently medication reminders arrangements should be forgotten.
  • good neighbor should not forget that the drug could harm him.

Question 12) Where to keep medicines ?

Drugs should be kept as specified in their label. Unless otherwise indicated, its recommended that drugs should be kept in a cool and dry place out of direct sunlight. Some of the drugs must be stored in the refrigerator at +4 ° C. These drugs should definitely not to be kept in the freezer and freeze.

Question 13) Is it right to collect remaining drugs in home from previous treatment to use in other patients ?

The unknown storage conditions of these drugs may decrease their effectiveness, they can become unstable or even toxic effects may occur. Therefore, for protecting public health, the re-use of these drugs is not suitable.

Question 14) Are medications indicated in flu and common cold.

Since common cold and flu are caused by viruses, antibiotics are not indicated in their treatment. Bed rest and plenty of fluid intake are the most effective treatment methods to stop disease progress and to prevent the spreading of infectious agents to the community.

Question 15) What should be considered while using antibiotics ?

Antibiotics which has the capacity to inhibit the growth of or to kill  bacteria are used to cure infections caused by them. They also ameliorate fever and other central systemic effects of infections.

Antibiotics is not indicatedin  diseases such as influenza, and their use can cause disruption of body flora.

Development of antibiotic resistance should be monitored and results of  microbiological tests should be reported to the professional persons.

Antibiotics should be use in accordance with physicians in pregnants and nursing mothers.

Question 16)  What to consider while taking vitamins?

Vitamins plays a key role in many physiological processes. For this reason, some vitamins must be obtained from food since they can not be synthesized by the human body. Healthy people do not need to take extra vitamin additional to their diet.  But vitamins may be needed in conditions of vitamin deficiency and increase in demand. Vitamins must be used according to the physician’s recommendation. Taking vitamins without consulting a physician and /or pharmasit is absolutely not true. Unnecessary use of vitamins can bring  more harm than good. Vitamins must be used rationally and correctly.

Question 17)  Questions to ask to physician and/or pharmacist before using medicine

  • How to prepare my medicine (dilution, dissolve in water, shaking)
  • How to use my medicine
  • Which times of the day and how many times should I take medicine
  • How long does my treatment take
  • Are there any food or drink to avoid in my diet during my treatment
  • What should I do if I encounter an adverse effect
  • How (which conditions) to store my medicine


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